Open access
Sep 2026
Topical sulforaphane exacerbates disease and promotes the accumulation of inflammatory CD8+ T cells in a dermatitis model
Background Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by skin barrier dysfunction and immune activation. Antioxidants such as sulforaphane (SFN) have shown benefit in mouse models of AD and are being explored as topical therapies. Objectives We investigated the immune mechanisms through...
A. Tukanowicz-Hassett, S. Bapat, Yuichi Yokoyama et al.
· bioRxiv · 0 citations