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T. Kinfe

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Preprint Aug 2026

Convergent Evolution in Neural Representation Space: Emergent Order in Deep Belief Networks

Deep Belief Networks (DBNs) learn hierarchical generative models without class supervision. Here, we ask whether this purely unsupervised process nevertheless organizes internal representations according to the unknown data classes. We analyze successive layers of DBNs trained on MNIST, Fashion-MNIST, and KMNIST using the Generalized Discrimination Value (GDV), supervised probes applied only after training, a reconstruction-based measure of abstraction distance, effective dimensionality, and free sample generation. Remarkably, class-specific clustering generally increases with depth across datasets and network widths, although no label information is available during DBN training. Control experiments show that this effect depends on the learned feature structure and cannot be explained by random transformations, weight marginals, dimensionality reduction, or sigmoid saturation. The first hidden layers also frequently make class identity more accessible to linear and nonlinear probes. With greater depth, representations become increasingly compact and prototype-like as neurons acquire correlated feature directions. At the same time, GDV and probe accuracy reveal complementary aspects of class structure: improved average clustering can coexist with reduced accessibility for a few difficult class pairs. These findings demonstrate that layer-wise generative learning can spontaneously uncover and progressively amplify class-related structure in unlabeled data.

Patrick Krauss, Achim Schilling, Andreas K. Maier et al. · 0 citations
Review Open access Aug 2026

Perspectives of Biophysical Therapies in Glioblastoma.

Biophysical therapies are best conceived as adjunctive tools within multimodal glioblastoma management rather than stand-alone solutions, with a strong focus on predictive biomarker-driven, mechanistically informed trial designs.

Jena Kim, L. Bunse, T. Kinfe et al. · 0 citations