BACKGROUND
Formal thought disorder (FTD) is a key determinant of social functioning in schizophrenia. However, existing syntheses have not differentiated positive versus negative FTD dimensions, which have distinct trajectories, mechanisms, and treatment implications. We examined the differential associations of positi...
Clara Benedetta Caterina Soldovieri, D. Elleuch, Jessica Ahrens et al.· Schizophrenia Research· 0 citations
Key Points Question Are gray matter volume (GMV) trajectories over the long-term course of major depressive disorder (MDD) associated with cumulative or acute illness severity? Findings In this 10-year case-control study including 206 participants, fronto-limbic GMV changes were significantly associated with individual...
A. Kraus, J. Goltermann, T. Borgers et al.· JAMA Network Open· 0 citations
The moderating effect of CR on the brain network-cognition association provides a neurobiological rationale for this vulnerability and supports incorporating CR into routine clinical assessment to guide risk stratification and personalized treatment planning.
M. Gruber, Henrike Renaud, M. Mauritz et al.· Psychotherapy and Psychosoma...· 0 citations
Major depressive disorder (MDD) has been associated with accelerated structural brain aging, yet whether this reflects a pre-existing neurobiological vulnerability, a dynamic acute state effect, or an accumulating biological residual remains unresolved. Across two longitudinal cohorts (N=3220), including a unique sampl...
M. Konowski, A. Kraus, J. Goltermann et al.· medRxiv· 0 citations
This study provides the first data-driven evidence for a potential causal role of gut microbiota in the pathophysiology of depression in humans, and employs state-of-the-art causal inference tools within Judea Pearl's framework.
L. Fehse, A. H. Ribeiro, N. Winter et al.· Gut microbes· 0 citations
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