Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor treatment options, emphasizing the need for novel therapeutic targets. Hub proteins have high connectivity (i.e., many interaction partners) and often act as central biological regulators. Here, we aimed to identify hub proteins with potential...
Foram Vyas, Virginie Defamie, Kelvin Yeung et al.· Cancer Research· 0 citations
Urine is an attractive biomarker analyte for non-invasive longitudinal monitoring of health and disease, particularly for diseases of the genitourinary tract, like prostate and bladder cancer. The composition of an individual's urine reflects both genetic and lifestyle characteristics that differ across geographies and...
Annie Ha, J. Arbet, Zhu-Yu Qiu et al.· Journal of the National Canc...· 0 citations
A lineage-resolved monolayer culture system is established that enables propagation of primary human mammary epithelial populations while preserving lineage identity across passages and provides a functional framework for determining critical events in the expansion of genomically altered mammary epithelial cells in th...