Author

T. Kovalenko

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Open access Sep 2026

Discovery and preclinical validation of a translationally optimized mitochondrial complex I modulator for Alzheimer’s disease

Findings establish mild modulation of mtCI as a therapeutic strategy to restore metabolic resilience and identify C273 as a promising disease-modifying candidate for AD treatment.

Sergey Trushin, Thi Kim Oanh Nguyen, Mark Ostroot et al. · npj Drug Discovery · 0 citations