Eastern equine encephalitis virus-vaccinated mice are protected against Madariaga virus despite negligible neutralizing antibody titers
Madariaga virus (MADV) is an understudied member of the eastern equine encephalitis virus (EEEV) complex that circulates widely in Latin America and may be geographically expanding. Spillover infections can cause severe disease in humans and equids. Despite these public and animal health concerns, no MADV vaccines or t...