Author

T. Manke

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Epigenetic perturbation unravels diverse origins, state conversions and de-differentiation of cortical astrocytes

DOT1L is established as a barrier between these astrocyte states, limiting differentiation of the astrocytes expressing phagocytosis marker genes, and lowering the DOT1L-mediated epigenetic barrier strongly favours appearance of astrocytes with limited phagocytosis properties and reactivation of progenitor programs.

Maira Mirza, Tobias Hohl, Camila L. Fullio et al. · bioRxiv · 0 citations

Open access Jul 2026

Transcription initiation drives dosage compensation establishment and maintenance in male Drosophila

Dosage compensation (DC) in Drosophila equalizes X chromosome–linked gene expression via the male-specific lethal complex, which acetylates histone 4 lysine-16 on the male X chromosome. How DC is established during early embryogenesis remains obscure, largely due to the difficulty of obtaining sufficient sex-specific m...

Ronald Oellers, A. Alexiadis, Yidan Sun et al. · Science Advances · 0 citations