Author

T. Milde

3 papers indexed here

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Open access Sep 2026

Interdisciplinary management and genetic evaluation of pediatric cancer predisposition syndromes: a retrospective cohort study.

The interdisciplinary CPS consultation model contributes to identifying hereditary cancer predisposition in pediatric patients and families and provides a scalable foundation for systematic CPS assessment and development of standardized, evidence-based surveillance protocols in pediatric oncology.

N. Dikow, Anna-Katharina Nitschke, S. Hirsch et al. · European Journal of Human Ge... · 0 citations

Aug 2025

O-mannosylation and protein maturation check-points represent therapeutic opportunities in BRAF fusion protein oncogenesis

Fusions between protein-coding genes are common oncogenic drivers across cancers, typically pairing a proto-oncogene with partner that does not independently drive cancer. In all therapeutically actionable fusions, the proto-oncogene is the drug target, the contributions to oncogenicity of the fusion partner have large...

Anna Borgenvik, Sean A. Misek, Daniel Christen et al. · bioRxiv · 1 citation

Open access Jul 2026

Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experience

By optimizing preanalytical and bioinformatic tools for pediatric settings, this study improved plasma-based cancer detection, molecular tumor characterization, and identification of targetable alterations, laying the groundwork for integration into personalized medicine programs and clinical trials.

K. Maass, P. Puranachot, S. Volz et al. · Genome Medicine · 0 citations