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Author

T. Miyakawa

3 papers indexed here

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Open access Sep 2026

350. Transcriptomic analysis of mouse brain tissue demonstrates similarity between sleep deprivation and neuronal hyperexcitation-induced gene expression

Abstract Background Sleep deprivation is associated with numerous health problems and has been linked to neuronal hyperexcitation, a potential driver of its neurological harm. Aims & Objectives This study aimed to elucidate the transcriptomic relationship between sleep deprivation and neuronal hyperexcitation. Method T...

M. M. Chatzigiannis, H. Hagihara, T. Miyakawa · 0 citations
Open access Jul 2026

Repetitive neuronal activation regulates cellular maturation state via nuclear reprogramming

Repeated stimulation of dentate gyrus neurons in mice reverts post-mitotic mature neurons to an immature-like state through reactivation of cell-cycle-like programs—a previously unrecognized form of cellular plasticity termed “nuclear reprogramming.”

Tomoyuki Murano, H. Hagihara, K. Tajinda et al. · 3 citations
Review Open access Jul 2026

Large-scale dimensional behavioral profiling dissociates fear memory from locomotor confounds in mice: The necessity of baseline-normalized metrics

It is shown that baseline locomotor normalization is essential for interpreting fear conditioning as a memory assay and provide an open framework for selecting and reporting locomotor-normalized metrics.

Daiki X. Sato, M. M. Chatzigiannis, Hirotaka Shoji et al. · 0 citations

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