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T. Mocking

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From signal to survival

Acute myeloid leukemia (AML) is a heterogeneous myeloid neoplasm characterized by uncontrolled proliferation of immature myeloid blasts. Although most patients treated with intensive chemotherapy can achieve a state of morphological remission, residual leukemic cells may remain in the bone marrow and are associated wit...

T. Mocking · 0 citations
Open access Sep 2026

Persistent IL-18 fuels expansion of CD38+HLA-DR+CD8+ T cells in Still's disease and macrophage activation syndrome.

OBJECTIVE Still's disease (SD) is an autoinflammatory disorder characterized by remarkably high IL-18 levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is asso...

Greta Rogani, R. Erkens, A. Bodelón et al. · 0 citations

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