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Author

T. Okamura

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Open access Sep 2026

CASTOR1 regulates humoral immune responses and contributes to the pathogenesis of systemic lupus erythematosus.

OBJECTIVES CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. METHODS We analyzed human B cell transcriptomes from healthy controls and patients with systemic lu...

T. Kusuda, T. Komai, T. Itamiya et al. · 0 citations

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