Author

T. Pandelani

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Review Open access Aug 2026

Post-MI Remodeling Mechanics of Left Ventricle: Microstructure-Informed Models, Identifiability, and Uncertainty for Patient-Specific Prediction

Background: Myocardial infarction (MI) causes spatially heterogeneous loss of contractility and progressive extracellular matrix remodeling, altering left ventricular mechanics from the acute phase through chronic remodeling. This review integrates current understanding of infarct, border-zone, and remote-myocardial mi...

T. Pandelani, F. Nemavhola · Bioengineering · 0 citations

Open access Aug 2026

GRAIL-heart: A graph attention network for inferring ligand-receptor interactions in spatial transcriptomics

GRAIL-Heart is presented, a graph-attention-based framework that integrates spatial tissue topology with multi-task learning to predict context-dependent L-R interactions, reconstruct gene expression, and infer causal signalling pathways in spatial transcriptomics data.

Tumo Kgabeng, Lu-Lu Wang, H. Ngwangwa et al. · MethodsX · 0 citations

Aug 2026

Development of novel Schiff Base-triazole hybrids with potent antimicrobial agent: Design, synthesis, in-silico and biological evaluation.

Findings position Schiff-base triazole hybrids as structurally versatile and biologically promising scaffolds, warranting accelerated pharmacological exploration toward the development of next-generation antimicrobial therapeutics.

Javed Khan, Anjali Rani, Mohd Aslam et al. · Bioorganic chemistry (Print) · 0 citations