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T. Roberts

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Review Open access Aug 2026

The role of molecular profiling for castration-resistant prostate cancer treatment and therapy development

Early-stage prostate cancer (PCa) is overwhelmingly driven by aberrant androgen receptor (AR) signalling. Accordingly, standard-of-care treatments include androgen deprivation therapy (ADT) and AR pathway inhibitors (ARPIs), with disease detection and therapy-response monitoring relying on blood-borne PSA, a product of...

Tim J. Mann, Therese M. Becker, T. Roberts et al. · 0 citations

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