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Author

T. Rusu

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Open access Sep 2026

Late-Diagnosed Cystic Fibrosis with Co-Occurring CFTR 3849+10kbC>T and 5T Variants: A Case Report

Background: The deep-intronic variant 3849+10kbC>T preserves residual CFTR function and is recurrently associated with pancreatic sufficiency, normal or borderline sweat chloride and diagnosis beyond early childhood. A co-occurring poly-T 5T allele adds a second layer of uncertainty: its penetrance depends on the TG re...

Paula Popovici, Adriana Mihai, L. Butnariu et al. · 0 citations
Review Open access Aug 2026

Molecular mechanisms of antibiotic resistance in Gram-positive and Gram-negative bacteria - a narrative review

Lariocidin, a structurally novel ribosome-targeting lasso peptide with broad-spectrum activity against both Gram-positive and Gram-negative multidrug-resistant pathogens, is presented as an emerging therapeutic scaffold that circumvents resistance mechanisms operating across both bacterial groups.

Denisa Claudia Tonco, C. Gavrilovici, Ancuța Lupu et al. · 1 citation

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