Circulating tumor HPV DNA reappearance as an early indicator of recurrence after radiotherapy-based treatment for HPV-associated oropharyngeal cancer: analysis of more than 2000 assessments in 232 patients.
BACKGROUND Circulating tumor human papillomavirus DNA (ctHPV DNA) is a promising blood-based surveillance biomarker in HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) and head-and-neck carcinoma of unknown primary (CUP). This study aimed to evaluate the diagnostic performance of ctHPV DNA-based molecular tes...