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T. Singh

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Review Open access 2026

Role of non-pharmacological cognition building techniques in delayed progression of Alzheimer's disease: A matter of blood-brain barrier dysfunction

Cognitive rehabilitation treatments for Alzheimer's disease and early-stage dementia are increasingly accessible to older adults and aim to slow the progressive decline in functional performance and cognitive abilities associated with ageing. Alzheimer's disease may involve disruption of affected brain systems, impaire...

S. Dhankhar, R. Gautam, Samrat Chauhan et al. · 0 citations
Review Oct 2026

The role of renin-angiotensin system modulation in the pathophysiology of neuropsychiatric disorders.

The renin-angiotensin system (RAS), traditionally recognized for cardiovascular and renal regulation, has emerged as a critical mechanistic player in neuropsychiatric pathophysiology. The brain possesses its own independent RAS with components located throughout limbic regions, cortical areas, and monoaminergic circuit...

Akhil Sharma, Tanya Goel, Ashi Mannan et al. · 0 citations
Review Open access Sep 2026

Recent medicinal chemistry efforts of targeting protein kinases for treating neurological conditions of Parkinson's and Alzheimer's diseases

The human genome encodes a wide variety of protein kinases that regulate multiple cellular functions. These enzymes play a crucial role in amplifying and propagating intracellular signals during signal transduction. Dysregulation of protein kinase signaling is associated with vascular diseases, inflammatory disorders,...

Rajwinder Kaur, D. K. Lang, Ankita Sood et al. · 0 citations
Review Aug 2026

The gut-kidney axis revisited: Integrating gut microbiota, autophagy and metabolomics in chronic kidney disease.

This model highlights how gut dysbiosis alters systemic metabolite profiles, how these metabolites regulate renal autophagic activity, and how impaired autophagy further promotes metabolic and inflammatory reprogramming in CKD progression.

Khemender Lidoo, Rupinder Kaur, Ravinder Singh et al. · 0 citations

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