Author

T. Siqueira

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Review Open access Oct 2026

MATERNAL VITAMIN B12 DEFICIENCY AND PERINATAL AND CHILD NEURODEVELOPMENTAL OUTCOMES: A SYSTEMATIC REVIEW AND META-ANALYSIS

Background: Vitamin B12 is essential for one-carbon metabolism, deoxyribonucleic acid (DNA) synthesis, and myelination, and inadequate maternal status during pregnancy may influence fetal growth and child neurodevelopment. Objective: To evaluate the association between maternal vitamin B12 status and perinatal and chil...

E. Carvalho, H. K. P. Sousa, T. Siqueira et al. · medRxiv · 0 citations

Review Open access Sep 2026

Efficacy of Testosterone Replacement Therapy in Men WithHypogonadism: A Systematic Review and Meta-Analysis of ClinicalOutcomes, Body Composition, and Quality of Life

Background: Male hypogonadism is associated with sexual, physical, and psychological manifestations, and testosterone replacement therapy (TRT) is used to restore testosterone levels and relieve symptoms. Objective: To evaluate the efficacy of TRT in adult men with hypogonadism across erectile function, hypogonadal sym...

T. Siqueira, H. K. Pereira Sousa, R. R. de Queiroz · medRxiv · 0 citations