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Open access Sep 2026

Protective effects of cannabidiol against acute stress: behavioral responses and corticosterone concentrations in female Wistar rats

Background Cannabidiol (CBD) has been widely investigated for its potential anxiolytic and stress-modulating effects. This study evaluated whether CBD reduces the stress response induced by acute restraint stress in rats. Methods Thirty-six female Wistar rats were randomly assigned to six groups. Four experimental grou...

M. Uršič, Mina Cansu Karaer, Alenka Gregorič et al. · 0 citations
Open access Sep 2026

Pharmacokinetics of Buccally Administered Cannabidiol and Oral Carprofen During Single- and Repeated-Dose Administration in Dogs.

Repeated dosing resulted in increasing 2-h post-dose CBD concentrations over time, and 7-COOH-CBD showed greater exposure and persistence than 7-OH-CBD, while carprofen pharmacokinetics were consistent with previous reports.

T. Vake, K. Tomsič, Žiga Žgank et al. · 0 citations

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