Author

T. Vaňková

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Open access Oct 2026

Transcriptomic analysis reveals distinct expression patterns in focal cortical dysplasia.

OBJECTIVE Focal cortical dysplasia (FCD) is a common cause of drug-resistant epilepsy in children and adults and exhibits substantial clinical and histopathological heterogeneity. However, morphological classification alone does not fully explain variability in epileptogenicity, disease severity, or treatment response....

Shivani Sonawane, M. Hendrych, M. Ručková et al. · Epilepsia · 0 citations

Open access Aug 2026

Glioblastoma organoids derived from patient tumor tissueas a model for studying extracellular communication and microRNAs in the tumor microenvironment.

Glioblastoma (GBM) is the most aggressive primary brain tumor in adult patients and is characterized by significant cellular heterogeneity and complex interactions between tumor cells and the tumor microenvironment. Extracellular vesicles (EVs) and the microRNAs (miRNAs) they carry are important mediators of intercellu...

Kamila Součková, F. Siegl, Martina Hýžďalová et al. · Klinicka onkologie · 0 citations