T. Wang

International case-control study of DNA methylation biomarkers for the minimally invasive diagnosis of esophageal squamous cell carcinoma.

BACKGROUND Esophageal squamous cell carcinoma (ESCC), the most common type of esophageal cancer worldwide, is usually diagnosed via esophagogastroduodenoscopy (EGD), an expensive procedure having limited availability in low- and Middle-Income countries (LMICs). We therefore developed diagnostic strategy that applies ES...

CRISPR-AMPED: A CRISPR/Cas-based immunoassay with attomolar sensitivity enabled by magnetic proximity extension and detection.

Defining the levels of the chromatin landscape using the I-CATCH system

The I-CATCH system has high analytical performance for measuring the levels of histone tail PTMs and the normalized levels of multiple histone tail PTMs at different genomic loci from both HeLa cells and human plasma are reported.