Open access
Aug 2026
OC5.4 - ECE_3532 - Constitutive active expression of ZFP36L1 in anterior pituitary SOX2+ stem cells results in pituitary hypoplasia and a failure of terminal differentiation via a non-cell autonomous mechanism
These experiments identify specific paracrine mediators required for terminal differentiation in the anterior pituitary, offering new molecular targets for efficient regenerative approaches and establish that ZFP36L1 regulation in PSCs is indispensable for pituitary organogenesis.
O. Sherwin, S. Manshaei, T. Willis et al.
· European Journal of Endocrin... · 0 citations