Author

Ting-Ting Xiao

2 papers indexed here

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Open access Sep 2026

Model-Informed Ceftazidime-Avibactam Dosing Stratified by Renal Function and Renal Replacement Therapy Status in Critically Ill Patients: A Prospective Population Pharmacokinetic and Monte Carlo Simulation Study

Introduction Carbapenem-resistant organisms (CROs) threaten critically ill patients, requiring model-informed ceftazidime-avibactam (CAZ-AVI) dosing by renal function and renal replacement therapy (RRT) status. Materials and Methods Thirty-three patients were prospectively enrolled at one center (18 RRT; 15 non-RRT). R...

Juan Hu, Chu-Hui Wang, Xiao-Juan Wang et al. · Drug Design, Development and... · 0 citations

Open access Aug 2026

Elevated wzc mutation frequency promotes carbapenem resistance evolution in hypervirulent Klebsiella pneumoniae ST23

ABSTRACT The worldwide expansion of carbapenemase-producing hypervirulent K. pneumoniae (CP-hvKP) raises serious concerns about potentially untreatable invasive infections. ST23, an archetypal hvKP clone, has been highlighted due to the rising prevalence of carbapenem resistance largely driven by horizontal plasmid tra...

Tao Chen, Xue-Ting Wang, Luying Xiong et al. · Emerging Microbes and Infect... · 0 citations