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Author

Taekjip Ha

2 papers indexed here

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Open access Sep 2026

A superfamily 1 helicase translocates on double-stranded DNA

To the knowledge, this is the first demonstration of processive dsDNA translocation by an SF1 helicase, and it broadens models for how translocases operate on DNA during replication and repair.

Sushil Pangeni, A. Nakara, Olivia Yang et al. · 0 citations
Open access Aug 2026

Direct visualization of MCM helicase activation and replisome coupling in situ

Deciphering the spatial organization of molecular machines that copy the genome remains a fundamental challenge in biology. Essential for eukaryotic DNA replication, Mini-Chromosome Maintenance (MCM2-7) helicases are loaded during G1 as double hexamers (DHs) to license replication origins. Upon activation in S phase, e...

O. Zinder, Jonas Zähringer, Hana Polasek-Sedlackova et al. · 0 citations

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