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Author

Tahir Tilki

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Open access Jul 2026

Novel Hydrazone Derivative with 4-(4-Aminophenoxy)-N-methylpicolinamide Moiety: Spectroscopic, Molecular Dynamics, and Docking Studies for Potential Anticancer Activity

A novel hydrazone incorporating the 4-(4-aminophenoxy)-N-methylpicolinamide pharmacophore is designed and syn-thesized to achieve selective kinase inhibition and confirmed lig-and–protein complex stability, minimal RMSD fluctuations, and consistent hydro-gen bond occupancy under physiological conditions.

T. Yeşil, Ömer Dilek, Tahir Tilki · 0 citations