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Author

Takahiro Bamba

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Open access Sep 2026

Coupling fatty acid biosynthesis to β-oxidation enhances the biosynthesis of malonyl-CoA-dependent polyketides.

Malonyl-CoA is a major extender unit in polyketide biosynthesis; however, in Escherichia coli, it is predominantly consumed by fatty acid biosynthesis, limiting its availability for heterologous polyketide production. Here, we engineered a fatty acid biosynthesis-β-oxidation carbon-recycling pathway (FABOX pathway) tha...

Takatoshi Suematsu, Shumpei Asamizu, Manami Takama et al. · 0 citations
Jul 2026

Metabolic Engineering of Microbial Strains for 1,2,4-Butanetriol Production: Progress and Future Perspectives.

This chapter focuses on research progress in metabolic engineering of BT production, which mainly includes design of BT biosynthetic pathways for expression in bacterial and yeast cell factories, current metabolic engineering and process optimization strategies to optimize BT production, and utilizing lignocellulosic b...

Weibin Wang, Mengrui Tao, Kai Li et al. · 0 citations

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