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Author

Takao Fujii

2 papers indexed here

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Open access Oct 2026

Clinical characteristics and severity classification in Mixed Connective Tissue Disease: a nationwide retrospective study.

OBJECTIVES To characterize clinical manifestations, major organ involvement, real-world treatment patterns, and factors associated with severity classification in Japanese patients with mixed connective tissue disease (MCTD), aiming to clarify its heterogeneous clinical spectrum. METHODS This nationwide retrospective...

S. Kubo, Yurie Kanda, Hideto Kameda et al. · 0 citations
Aug 2026

Adult Hypophosphatasia with a Single Heterozygous c.572A>G p.Glu191Gly Mutation in the ALPL gene: Case Report.

Adult-onset hypophosphatasia manifests after age 18, and is characterized by reduced tissue-nonspecific alkaline phosphatase (ALP) activity. This can lead to fractures, pseudo-fractures, osteomalacia, decreased bone density (bone loss), muscle weakness, myalgia, arthralgia, headache, dental symptoms (loss of permanent...

Kota Hyakuna, Shigeru Iwata, Taro Nishikawa et al. · 0 citations

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