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Author

Takayuki Otsubo

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Open access Jul 2026

A compact minimal promoter-feedback circuit enables enhanced oviduct-restricted transgene expression in chickens.

Precise spatial restriction of transgene expression is essential for safe in vivo production of bioactive proteins; however, regulatory elements that confer tissue specificity often span large genomic regions and are incompatible with size-limited viral vectors. Here, we report a compact synthetic promoter-feedback cir...

Yoshinori Kawabe, Takayuki Otsubo, Reina Obata et al. · 0 citations

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