Oct 2026
Lipid-mediated activation of BLT2 promotes membrane repair to prevent cell death.
Yuan Chi, Kazuko Saeki, K. Yasukawa et al.
· Journal of Cell Biology · 0 citations
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Sep 2026
PLCXD2 preferentially hydrolyzes phosphatidylinositol and supports retinal lipid homeostasis and photoreceptor integrity
PLCXD proteins have been linked to phosphoinositide metabolism for more than a decade, and PLCXD2 activity has been associated with phosphatidylinositol 4,5-bisphosphate [PI(4,5)P₂] depletion, yet its preferred direct substrate has remained unresolved. Here, cellular lipidomics showed that catalytically active PLCXD2 r...
Kaori Kanemaru, Wako Iwata, Akira Katayanagi et al.
· bioRxiv · 0 citations