Open access
Sep 2026
Step-by-step maturation mechanism of the binary toxin pore revealed by cryo-EM analysis.
Membrane pore-forming proteins (PFPs) form ring-shaped membrane-translocating oligomers on membranes, contributing to infection, immunity, and cell death functions. Binary toxins produced by some bacteria consist of an enzymatic component that acts as a toxin and a membrane-binding component that forms a pore that deli...
Tomohito Yamada, Ren Nakanishi, Yukihiko Sugita et al.
· Proceedings of the National... · 0 citations