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Takujiro Homma

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Review Open access Sep 2026

Interferon-Stimulated Gene-Mediated Defense Against Prion Infection: Noncanonical Function of Oas1a

Prion diseases are invariably fatal neurodegenerative disorders characterized by the conformational conversion of the host-encoded prion protein (PrPC) into its misfolded, pathogenic isoform (PrPSc). Unlike conventional infectious agents such as viruses, prions lack nucleic acids, leading to the long-held assumption th...

Takujiro Homma, Daisuke Ishibashi · 0 citations

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