Author

Tal Ishon

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Open access Sep 2026

PRISM-GEP: Viewing Single-Cell Expression through the Lens of Topic Modeling.

MOTIVATION Gene-expression programs (GEPs) are the co-regulated gene modules whose coordinated activity encodes biological processes. Recovering them from single-cell RNA-seq is hard because regulation is many-to-many. A cell can run several programs at once, and a gene can take part in several. Methods that resolve pr...

Yanir Buznah, Tal Ishon, Uri Shaham · Bioinformatics · 0 citations