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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Tala Abu Arja

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Open access Oct 2026

MLH1 p.His112Arg Variant Is Associated With Increased Cancer Susceptibility.

Lynch syndrome, a prevalent hereditary cancer predisposition, is frequently caused by pathogenic variants in the MutL homolog 1 (MLH1) mismatch repair gene. However, a significant proportion of MLH1 missense variants remain classified as variants of uncertain significance (VUS), creating clinical ambiguity. Functional...

Amal Elfatih, Issam Tout, N. Doha et al. · 0 citations

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