Open access
Aug 2026
Antibody-mediated inhibition of ADAMTS-7 reduces experimental atherosclerosis
Objective One of the strongest genetic associations with coronary artery disease (CAD) risk maps to the metalloproteinase ‘a disintegrin and metalloproteinase with thrombospondin motifs 7’ (ADAMTS-7) locus. The protein was shown to promote plaque formation and instability. We aimed to generate and evaluate an antibody-...
M. A. Sharifi, Johannes Riechel, Michael Winkler et al.
· bioRxiv · 0 citations