Aug 2026
KLF6-driven macrophage-to-myofibroblast transition promotes PD-L1-mediated immune evasion in bladder cancer.
This study provides the first multi-omics characterization of MMT in bladder cancer, identifies KLF6 as a previously unrecognized driver of this transition, and demonstrates that KLF6-driven MMT upregulates tumour PD-L1 through intercellular crosstalk.
Yuwen Chen, Zi-Huan Wang, Cheng-Wu He et al.
· International Immunopharmaco... · 0 citations