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Review Open access Oct 2026

Crosstalk between gut microbiota-associated metabolites and adaptive immunity in cholecystitis: a conceptual mechanistic framework and potential therapeutic implications

The pathogenesis of cholecystitis involves the complex interplay of bile stasis, microbial dysbiosis, metabolic disturbances, and immune responses. Gut microbiota-associated metabolites can modulate adaptive immune components, including T helper 17 (Th17) cells, regulatory T (Treg) cells, CD8 + T cells, and B cells...

Xin-Qi Wang, Tao Zhang, Zhe-Tan Ren et al. · 0 citations
Review Open access Aug 2026

Microbiota-associated metabolic networks in gut-kidney communication and renal immune regulation: mechanisms and therapeutic potential

Current evidence linking microbiota-associated metabolic networks to renal immune remodeling across different kidney diseases is summarized, highlighting metabolite origin, shared target-cell responses, disease-specific and context-dependent mechanisms, and current evidence limitations.

Hong-Kun Zhang, Tao Zhang, Zheng-Chao Pan et al. · 0 citations

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