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Author

Taotao Tan

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Open access Aug 2026

Defining the Early Response of Oligodendrocyte-Lineage Cells to Traumatic CNS Axonal Injury.

Injured central nervous system axons rarely regenerate or remyelinate efficiently. Oligodendrocyte (OL) -lineage cells influence both processes, yet their early response to axonal injury remains incompletely defined. Using an optic nerve crush model in male and female mice, we profiled acute OL-lineage responses over t...

Yu Wu, Xiaoyun Ding, Jiaxing Li et al. · 0 citations
Open access Jul 2026

Kernelized approach enables explainable gene prioritizations for complex traits

K-PoPS provides a post hoc framework for examining and interpreting GWAS effector-gene nominations by decomposing each prediction into contributions from training genes, and identifies multiple plausible effector genes within a dilated cardiomyopathy locus contrary to the parsimonious assumption.

Tao-Tao Tan, M. Samee · 0 citations

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