Author

Terence E. Hébert

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Open access Sep 2026

Evaluating and comparing the signalling and functional landscape of hiPSC-CMs derived from patients with dilated cardiomyopathy

Non-ischaemic or dilated cardiomyopathy (DCM) is characterised by abnormal enlargement of the left ventricle, compromising the ability of the heart to pump blood to the body. All patients with DCM are offered the same treatment regimen regardless of individual differences, with highly variable results on disease progre...

Giada Castagnola, Diego Loggia, Kyla Bourque et al. · npj Biomedical Innovations · 0 citations

Open access Aug 2026

Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasion.

Loss of the orphan GPCR GPR52 in human breast cell lines leads to increased cell clustering, hybrid/partial EMT, and increased tumour burden in zebrafish, further expanding the understanding of mechanisms driving cancer progression and opening the door to novel therapeutic approaches.

Sarah Z. Hanif, Caleb Kutz, C. C. Au et al. · British Journal of Cancer · 0 citations