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Author

Tetsuhiro S. Hatakeyama

2 papers indexed here

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Preprint Sep 2026

Anomalous First Passage in Evolution: Edge-KPZ Theory

The pace of evolution depends on how rapidly new phenotypes arise. We show that neutral Wright-Fisher evolution exhibits anomalous first passage despite diffusive mutations. The mean time for the first individual to reach a prescribed phenotypic distance scales approximately as $(\sigma^2)^{-3/2}$ with mutation varianc...

Tetsuhiro S. Hatakeyama · 0 citations
Preprint Aug 2026

Global geometry of the genotype-phenotype map illuminates a trade-off between penetrance and mutational adaptability

An abstract model of stochastic genotype-phenotype mapping, inspired by interacting spins in statistical physics, permits exhaustive reconstruction of the map and finds that high-penetrance genotypes tend to occupy the interior of environment-specific high-fitness regions and are mutationally robust, whereas lower-pene...

Y. Ikeda, Kunihiko Kaneko, Tetsuhiro S. Hatakeyama · 0 citations

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