Thais A. Enoki

Domains or no domains? That is the question: insights from asymmetric bilayer models into plasma membrane lipid organization

The mammalian plasma membrane is characterized by its pronounced lipid asymmetry, including the exceptional enrichment of sphingomyelin (SM) in the exoplasmic leaflet. How this asymmetry influences cholesterol distribution and membrane organization remains a central and unresolved question in cell biology. The lipid...