Novel hydrazone-linked pyridin-1-ium salts as multi-targeted agents for Alzheimer's disease: design, synthesis, in vitro and in silico studies.
Hydrazone-linked pyridin-1-ium salts are highlighted as promising scaffolds for developing compact multi-targeted agents for AD by integrating key pharmacophores of acetylcholinesterase and β-secretase 1 inhibitors into a compact scaffold.