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Thomas Colson

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Open access Sep 2026

Design and Evaluation of Selective Positive Allosteric Modulators Targeting Kainate Receptors

Kainate-type ionotropic glutamate receptors (KARs) are emerging therapeutic targets for the modulation of excitatory neurotransmission in epilepsy, psychiatric disorders, and neurodegenerative diseases, yet selective positive allosteric modulators (PAMs) remain scarce. Starting from the benzothiadiazine AMPA receptor (...

Thomas Colson, Yasmin Bay, A. Manos-Turvey et al. · 0 citations

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