Autoimmune diseases such as primary Sjögren’s disease (pSjD) and systemic lupus erythematosus (SLE) share clinical and serological features, including type I interferon signatures, autoantibody formation, and chronic inflammation, but the underlying immunopathology is not the same. To support the development of tar...
F. Szelinski, Ana-Luisa Stefanski, A. Wiedemann et al.· Frontiers in Immunology· 0 citations
Identifying immune features that distinguish asymptomatic autoantibody-positive at-risk individuals from patients with established autoimmune disease is key to understanding the evolution from autoreactivity to established autoimmune disease. This study investigated immune characteristics of anti-SSA–positive at-ri...
J. Ritter, Ana-Luisa Stefanski, A. Aue et al.· Frontiers in Immunology· 0 citations
CD19 CAR T cells showed acceptable short-term tolerability in patients with treatment-refractory RA, justifying further evaluation, and the primary endpoint was met, allowing advancement to phase 2.
F. Albach, Marie C. Rehm, M. Hütter-Krönke et al.· Nature Medicine· 0 citations
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