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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Thomas Hartung

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Review Open access Aug 2026

Brain organoids in Alzheimer disease and related tauopathies: Challenges and opportunities for translational readiness

Summary A major hurdle in Alzheimer disease research is the failure of mouse models to capture complexities of the human brain that contributes to repeated clinical trial failure. Although the recent US Food and Drug Administration (FDA) Modernization Act 2.0 has enabled non-animal preclinical pathways, brain organoid...

A. Guruacharya, Thomas Hartung, Roberta Souza dos Reis et al. · 0 citations

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