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Thomas J. Sharpton

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Open access Sep 2026

A practical risk framework for large language model use in life science research

It is argued that effective prompt design is itself a primary risk management strategy, reducing the probability and severity of characteristic failures before verification is required, and introduced a structured framework for matching downstream verification effort to risk across dimensions of output verifiability, r...

Thomas J. Sharpton, Edward W. Davis Ii, Alexandra Alexiev · 0 citations

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