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Thomas J. Wilkinson

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Review Open access Sep 2026

Beyond weight loss: a narrative review of tirzepatide's impact on muscle and lean mass in people with overweight and obesity.

Tirzepatide, a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, has demonstrated substantial efficacy for weight loss in individuals with overweight and obesity. However, the extent to which this weight reduction affects lean mass remains unclear. This review evaluates cur...

Thomas J. Wilkinson, Rishada Ramzan · 0 citations

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