Open access
Oct 2026
Disease-associated NK-cell state remodeling reveals transcriptional profiles predictive of clinical phenotypes
Natural killer (NK) cells adapt their cellular states to diverse tissue and inflammatory environments, yet how this plasticity manifests across pathological contexts and relates to patient-level disease phenotypes remains poorly defined. Here we established the Human NK-cell Atlas (HNKA) from over 1 million NK cells, i...
F. Meng, Pei-Ran Lin, Shun-Jie Zhang et al.
· bioRxiv · 0 citations