Tian-Hui Hao

Chemoenzymatic Assembly of Branch-Selective Sulfated N- and O-Glycans to Decode Glycan-Binding Protein Recognition.

N- and O-glycosylations are essential post-translational modifications involved in numerous physiological and pathological processes. Sulfated N- and O-glycans, commonly found on biologically important glycoproteins, serve as critical mediators of molecular recognition. However, their precise structure-function relatio...