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Tian Mi

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Open access Jul 2026

Epigenetic mechanisms controlling longevity of T cell immunity 2259637

The findings show that Dnmt3a KO T cells have increased T cell stemness and durability and indicate that Dnmt3a drives CD8 T cell memory capacity during iterative acute stimulation, providing an epigenetic mechanism to improve immune durability.

Yun Liu, Ben Youngblood, Caitlin C. Zebley et al. · 0 citations
Open access Jul 2026

Targeting the Adenosine—Adenosine Deaminase-1 Axis to Restore HIV-Specific CD8+ T Cell Function 2309228

This approach provides a framework for targeting ADO-mediated immune suppression of CD8+T cells in HIV and other disease landscapes, including cancer, and establishes targeted ADA-1 delivery as a novel strategy to enhance CD8+ T-cell function.

Arden O. Edgerton, Dillon O'Neill, David Joyner et al. · 0 citations

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