Protein Generative Models (PGMs) have revolutionized structural biology by enabling the design of complex 3D protein structures from sequence data. However, this breakthrough introduces a dual-use challenge, exposing high-value PGMs to economic risks like unauthorized model extraction and biosecurity threats such as bi...
Hua-Jie Chen, Xin Guo, Yuchen Shi et al.· 0 citations
It is found that the refusal-related signal of LRMs drops sharply at the first generated token under harmful queries, which is associated with unsafe response generation, and this work proposes SafeToken, a lightweight inference-time intervention that injects a learned continuous safety anchor precisely at reasoning on...
Yi-Zheng Yang, Hai-Ning Yu, Yue-Chen Wang et al.· 0 citations
Experimental results demonstrate that RISA improves refusal reliability while largely preserving model utility, offering a practical solution for response-aware refusal calibration in LLMs.
Wenhan Chang, Tian-Qing Zhu, P. Xiong et al.· 0 citations
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