Chitosan-trimethoprim injectable hydrogel for anti-biofilm and chronic wound healing.
Schiff-base hydrogels are widely used as drug depots. However, their application in antibacterial wound healing is rarely explored. To fill this gap, we developed an injectable chitosan (CS) hydrogel physically loaded with trimethoprim (TMP) within a Schiff-base crosslinked network. The key novelty lies in the covalent...